Chronic obstructive pulmonary disease (COPD): We investigate the cellular and molecular basis of Chronic Obstructive Pulmonary Disease (COPD) to develop more effective treatments. Our research explores how environmental triggers, such as cigarette smoke and air pollution, damage the lungs and accelerate the aging process of lung cells. By studying chronic inflammation and cellular senescence, his team aims to develop new therapeutic interventions.
Key research areas in COPD:
Inflammation and oxidative stress: our research explores how pollutants induce chronic inflammation and oxidative stress in the lungs, which are central to the pathogenesis of COPD.
Cellular senescence: our work investigates the role of cellular senescence (cell aging) in COPD and its contribution to lung damage and hindered lung recovery.
Novel therapies: we are focused on developing new treatments to combat the effects of inflammation and cellular damage, which are not effectively addressed by current therapies. This includes testing new drug delivery methods and agents like curcumin to manage COPD induced by cigarette smoke.
Host-pathogen interactions: The research also examines how viral infections, such as SARS-CoV-2, can affect patients with COPD and potentially lead to more severe lung conditions.